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Probing of miniPEGγ-PNA-DNA Hybrid Duplex Stability with AFM Force Spectroscopy
Peptide nucleic acids (PNA) are synthetic polymers, the neutral peptide backbone of which provides elevated stability to PNA-PNA and PNA-DNA hybrid duplex. It was demonstrated that incorporation of diethylene glycol (miniPEG) at the γ position of the peptide backbone increased the thermal stability...
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| Pubblicato in: | Biochemistry |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4792705/ https://ncbi.nlm.nih.gov/pubmed/26898903 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b01250 |
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