Characterization and comparative analysis of 2,4-toluene diisocyanate and 1,6-hexamethylene diisocyanate haptenated human serum albumin and hemoglobin

Diisocyanates (dNCOs) are low molecular weight chemical sensitizers that react with autologous proteins to produce neoantigens. dNCO-haptenated proteins have been used as immunogens for generation of dNCO-specific antibodies and as antigens to screen for dNCO-specific antibodies in exposed individua...

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Detalhes bibliográficos
Publicado no:J Immunol Methods
Main Authors: Mhike, Morgen, Hettick, Justin M., Chipinda, Itai, Law, Brandon F., Bledsoe, Toni A., Lemons, Angela R., Nayak, Ajay P., Green, Brett J., Beezhold, Donald H., Simoyi, Reuben H., Siegel, Paul D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4792703/
https://ncbi.nlm.nih.gov/pubmed/26853746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2016.02.005
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