Hypomethylation within Gene Promoter Regions and Type 1 Diabetes in Discordant Monozygotic Twins

Genetic susceptibility to type 1 diabetes (T1D) is well supported by epidemiologic evidence; however, disease risk cannot be entirely explained by established genetic variants identified so far. This study addresses the question of whether epigenetic modification of the inherited DNA sequence may co...

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Pubblicato in:J Autoimmun
Autori principali: Elboudwarej, Emon, Cole, Michael, Briggs, Farren B.S., Fouts, Alexandra, Fain, Pamela R., Quach, Hong, Quach, Diana, Sinclair, Elizabeth, Criswell, Lindsey A., Lane, Julie A., Steck, Andrea K., Barcellos, Lisa F., Noble, Janelle A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4792657/
https://ncbi.nlm.nih.gov/pubmed/26782299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2015.12.003
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