Suppression of tumor angiogenesis by metformin treatment via a mechanism linked to targeting of HER2/HIF-1α/VEGF secretion axis

Anti-angiogenesis is currently considered as one of the major antitumor strategies for its protective effects against tumor emergency and later progression. The anti-diabetic drug metformin has been demonstrated to significantly inhibit tumor angiogenesis based on recent studies. However, the mechan...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Wang, Jichang, Li, Guangyue, Wang, Yaochun, Tang, Shouching, Sun, Xin, Feng, Xuefei, Li, Yan, Bao, Gang, Li, Pingping, Mao, Xiaona, Wang, Maode, Liu, Peijun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2015
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Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4792577/
https://ncbi.nlm.nih.gov/pubmed/26625311
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