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Development of Sunitinib in Hepatocellular Carcinoma: Rationale, Early Clinical Experience, and Correlative Studies

The approval of a multitargeted receptor tyrosine kinase inhibitor, sorafenib, with activity against vascular endothelial growth factor receptor-2 and -3, Raf-1 and B-Raf, platelet-derived growth factor receptor-α and -β, and other kinases, has ushered in the era of molecular targeted agents in adva...

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Bibliografske podrobnosti
izdano v:Cancer J
Main Authors: Zhu, Andrew X., Duda, Dan G., Sahani, Dushyant V., Jain, Rakesh K.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4792519/
https://ncbi.nlm.nih.gov/pubmed/19672141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PPO.0b013e3181af5e35
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