Application of aziridinium ring opening for preparation of optically active diamine and triamine analogues: Highly efficient synthesis and evaluation of DTPA-based MRI contrast enhancement agents

Ring opening of aziridinium ions with nitrogen nucleophiles was applied to the highly efficient synthesis of optically active vicinal diamines and diethylene triamine pentaacetic acid (DTPA) analogues as potential magnetic resonance imaging (MRI) contrast enhancement agents. The synthetic method fea...

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Publicado en:RSC Adv
Autores principales: Sun, Xiang, Chen, Yunwei, Wu, Ningjie, Kang, Chi Soo, Song, Hyun A, Jin, Shengnan, Fu, Yao, Bryant, Henry, Frank, Joseph A., Chong, Hyun-Soon
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4792306/
https://ncbi.nlm.nih.gov/pubmed/26989478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C5RA11306G
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