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The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs

The platinum drugs, cisplatin, carboplatin, and oxaliplatin, prevail in the treatment of cancer,, but new platinum agents have been very slow to enter the clinic. Recently, however, there has been a surge of activity, based on a great deal of mechanistic information, aimed at developing non-classica...

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Pubblicato in:Chem Rev
Autori principali: Johnstone, Timothy C., Suntharalingam, Kogularamanan, Lippard, Stephen J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4792284/
https://ncbi.nlm.nih.gov/pubmed/26865551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrev.5b00597
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