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The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs

The platinum drugs, cisplatin, carboplatin, and oxaliplatin, prevail in the treatment of cancer,, but new platinum agents have been very slow to enter the clinic. Recently, however, there has been a surge of activity, based on a great deal of mechanistic information, aimed at developing non-classica...

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Bibliographic Details
Published in:Chem Rev
Main Authors: Johnstone, Timothy C., Suntharalingam, Kogularamanan, Lippard, Stephen J.
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4792284/
https://ncbi.nlm.nih.gov/pubmed/26865551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrev.5b00597
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