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β-amyloid, hippocampal atrophy and their relation to longitudinal brain change in cognitively normal individuals

Recent literature has examined baseline hippocampal volume and extent of brain amyloidosis to test potential synergistic effects on worsening cognition and extent of brain atrophy. Use of hippocampal volume in prior studies was based on the notion that limbic circuit degeneration is an early manifes...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Neurobiol Aging
Hauptverfasser: Fletcher, Evan, Villeneuve, Sylvia, Maillard, Pauline, Harvey, Danielle, Reed, Bruce, Jagust, William, DeCarli, Charles
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4792128/
https://ncbi.nlm.nih.gov/pubmed/26973117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2016.01.133
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