Association between chronic stress-induced structural abnormalities in Ranvier nodes and reduced oligodendrocyte activity in major depression

Repeated stressful events are associated with the onset of major depressive disorder (MDD). We previously showed oligodendrocyte (OL)-specific activation of the serum/glucocorticoid-regulated kinase (SGK)1 cascade, increased expression of axon-myelin adhesion molecules, and elaboration of the oligod...

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Udgivet i:Sci Rep
Main Authors: Miyata, Shingo, Taniguchi, Manabu, Koyama, Yoshihisa, Shimizu, Shoko, Tanaka, Takashi, Yasuno, Fumihiko, Yamamoto, Akihide, Iida, Hidehiro, Kudo, Takashi, Katayama, Taiichi, Tohyama, Masaya
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4791682/
https://ncbi.nlm.nih.gov/pubmed/26976207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23084
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