Association between chronic stress-induced structural abnormalities in Ranvier nodes and reduced oligodendrocyte activity in major depression

Repeated stressful events are associated with the onset of major depressive disorder (MDD). We previously showed oligodendrocyte (OL)-specific activation of the serum/glucocorticoid-regulated kinase (SGK)1 cascade, increased expression of axon-myelin adhesion molecules, and elaboration of the oligod...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Miyata, Shingo, Taniguchi, Manabu, Koyama, Yoshihisa, Shimizu, Shoko, Tanaka, Takashi, Yasuno, Fumihiko, Yamamoto, Akihide, Iida, Hidehiro, Kudo, Takashi, Katayama, Taiichi, Tohyama, Masaya
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4791682/
https://ncbi.nlm.nih.gov/pubmed/26976207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23084
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