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Bone Morphogenetic Protein-focused Strategies to Induce Cytotoxicity in Lung Cancer Cells

BACKGROUND: High bone morphogenetic protein (BMP)-2 expression in lung carcinoma correlates with poor patient prognosis. The present study explored strategies to repress BMP signaling. MATERIALS AND METHODS: The cytotoxicity of BMP2-knockdown, dorsomorphin derivatives, and microRNAs was tested in tr...

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Publicat a:Anticancer Res
Autors principals: FOTINOS, ANASTASIOS, NAGARAJAN, NARAYANI, MARTINS, ADRIANO S., FRITZ, DAVID T., GARSETTI, DIANE, LEE, ANNETTE T., HONG, CHARLES C., ROGERS, MELISSA B.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4791537/
https://ncbi.nlm.nih.gov/pubmed/24778011
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