Molecular and functional interactions between AKT and SOX2 in breast carcinoma

The transcription factor SOX2 is a key regulator of pluripotency in embryonic stem cells and plays important roles in early organogenesis. Recently, SOX2 expression was documented in various cancers and suggested as a cancer stem cell (CSC) marker. Here we identify the Ser/Thr-kinase AKT as an upstr...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Schaefer, Thorsten, Wang, Hui, Mir, Perihan, Konantz, Martina, Pereboom, Tamara C., Paczulla, Anna M., Merz, Britta, Fehm, Tanja, Perner, Sven, Rothfuss, Oliver C., Kanz, Lothar, Schulze-Osthoff, Klaus, Lengerke, Claudia
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4791249/
https://ncbi.nlm.nih.gov/pubmed/26498353
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