Targeting CXCR1 on breast cancer stem cells: signaling pathways and clinical application modelling

In breast cancer it has been proposed that the presence of cancer stem cells may drive tumor initiation, progression and recurrences. IL-8, up-regulated in breast cancer, and associated with poor prognosis, increases CSC self-renewal in cell line models. It signals via two cell surface receptors, CX...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Brandolini, Laura, Cristiano, Loredana, Fidoamore, Alessia, De Pizzol, Maria, Di Giacomo, Erica, Florio, Tiziana Marilena, Confalone, Giuseppina, Galante, Angelo, Cinque, Benedetta, Benedetti, Elisabetta, Ruffini, Pier Adelchi, Cifone, Maria Grazia, Giordano, Antonio, Alecci, Marcello, Allegretti, Marcello, Cimini, Annamaria
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4791238/
https://ncbi.nlm.nih.gov/pubmed/26517518
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