Nucleolin antagonist triggers autophagic cell death in human glioblastoma primary cells and decreased in vivo tumor growth in orthotopic brain tumor model

Nucleolin (NCL) is highly expressed in several types of cancer and represents an interesting therapeutic target. It is expressed at the plasma membrane of tumor cells, a property which is being used as a marker for several human cancer including glioblastoma. In this study we investigated targeting...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Benedetti, Elisabetta, Antonosante, Andrea, d'Angelo, Michele, Cristiano, Loredana, Galzio, Renato, Destouches, Damien, Florio, Tiziana Marilena, Dhez, Anne Chloé, Astarita, Carlo, Cinque, Benedetta, Fidoamore, Alessia, Rosati, Floriana, Cifone, Maria Grazia, Ippoliti, Rodolfo, Giordano, Antonio, Courty, José, Cimini, Annamaria
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747212/
https://ncbi.nlm.nih.gov/pubmed/26540346
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