IL-27 induces the expression of IDO and PD-L1 in human cancer cells

IL-27 is a member of the IL-12 family that is produced by macrophages and dendritic cells. IL-27 inhibits the growth and invasiveness of different cancers and therefore represents a potential anti-tumor agent. By contrast, it may exert immune-regulatory properties in different biological systems. We...

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Pubblicato in:Oncotarget
Autori principali: Carbotti, Grazia, Barisione, Gaia, Airoldi, Irma, Mezzanzanica, Delia, Bagnoli, Marina, Ferrero, Simone, Petretto, Andrea, Fabbi, Marina, Ferrini, Silvano
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2015
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Research Paper: Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4791231/
https://ncbi.nlm.nih.gov/pubmed/26657115
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