Activation of an endothelial Notch1-Jagged1 circuit induces VCAM1 expression, an effect amplified by interleukin-1β

The Notch1 and Notch4 signaling pathways regulate endothelial cell homeostasis. Inflammatory cytokines induce the expression of endothelial adhesion molecules, including VCAM1, partly by downregulating Notch4 signaling. We investigated the role of endothelial Notch1 in this IL-1β-mediated process. B...

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Argitaratua izan da:Oncotarget
Egile Nagusiak: Verginelli, Federica, Adesso, Laura, Limon, Isabelle, Alisi, Anna, Gueguen, Marie, Panera, Nadia, Giorda, Ezio, Raimondi, Lavinia, Ciarapica, Roberta, Campese, Antonio F., Screpanti, Isabella, Stifani, Stefano, Kitajewski, Jan, Miele, Lucio, Rota, Rossella, Locatelli, Franco
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Impact Journals LLC 2015
Gaiak:
Research Paper: Pathology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4791227/
https://ncbi.nlm.nih.gov/pubmed/26646450
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