CXCL13 is a plasma biomarker of germinal center activity

Significantly higher levels of plasma CXCL13 [chemokine (C-X-C motif) ligand 13] were associated with the generation of broadly neutralizing antibodies (bnAbs) against HIV in a large longitudinal cohort of HIV-infected individuals. Germinal centers (GCs) perform the remarkable task of optimizing B-c...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Havenar-Daughton, Colin, Lindqvist, Madelene, Heit, Antje, Wu, Jennifer E., Reiss, Samantha M., Kendric, Kayla, Bélanger, Simon, Kasturi, Sudhir Pai, Landais, Elise, Akondy, Rama S., McGuire, Helen M., Bothwell, Marcella, Vagefi, Parsia A., Scully, Eileen, Tomaras, Georgia D., Davis, Mark M., Poignard, Pascal, Ahmed, Rafi, Walker, Bruce D., Pulendran, Bali, McElrath, M. Juliana, Kaufmann, Daniel E., Crotty, Shane
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2016
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4790995/
https://ncbi.nlm.nih.gov/pubmed/26908875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1520112113
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