Promiscuous Recognition of a Trypanosoma cruzi CD8(+) T Cell Epitope among HLA-A2, HLA-A24 and HLA-A1 Supertypes in Chagasic Patients

BACKGROUND: TcTLE is a nonamer peptide from Trypanosoma cruzi KMP-11 protein that is conserved among different parasite strains and that is presented by different HLA-A molecules from the A2 supertype. Because peptides presented by several major histocompatibility complex (MHC) supertypes are potent...

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Bibliographic Details
Published in:	PLoS One
Main Authors:	Lasso, Paola, Beltrán, Lina, Guzmán, Fanny, Rosas, Fernando, Thomas, M. Carmen, López, Manuel Carlos, González, John Mario, Cuéllar, Adriana, Puerta, Concepción J.
Format:	Artigo
Language:	Inglês
Published:	Public Library of Science 2016
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4790940/ https://ncbi.nlm.nih.gov/pubmed/26974162 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150996
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Promiscuous Recognition of a Trypanosoma cruzi CD8(+) T Cell Epitope among HLA-A2, HLA-A24 and HLA-A1 Supertypes in Chagasic Patients

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