Trypanosoma cruzi vaccine candidate antigens Tc24 and TSA-1 recall memory immune response associated with HLA-A and -B supertypes in Chagasic chronic patients from Mexico

Trypanosoma cruzi antigens TSA-1 and Tc24 have shown promise as vaccine candidates in animal studies. We evaluated here the recall immune response these antigens induce in Chagasic patients, as a first step to test their immunogenicity in humans. We evaluated the in vitro cellular immune response af...

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Udgivet i:PLoS Negl Trop Dis
Main Authors: Villanueva-Lizama, Liliana E., Cruz-Chan, Julio V., Aguilar-Cetina, Amarú del C., Herrera-Sanchez, Luis F., Rodriguez-Perez, Jose M., Rosado-Vallado, Miguel E., Ramirez-Sierra, Maria J., Ortega-Lopez, Jaime, Jones, Kathryn, Hotez, Peter, Bottazzi, Maria Elena, Dumonteil, Eric
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5805372/
https://ncbi.nlm.nih.gov/pubmed/29377898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0006240
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