Correlation of Utrophin Levels with the Dystrophin Protein Complex and Muscle Fibre Regeneration in Duchenne and Becker Muscular Dystrophy Muscle Biopsies

Duchenne muscular dystrophy is a severe and currently incurable progressive neuromuscular condition, caused by mutations in the DMD gene that result in the inability to produce dystrophin. Lack of dystrophin leads to loss of muscle fibres and a reduction in muscle mass and function. There is evidenc...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Janghra, Narinder, Morgan, Jennifer E., Sewry, Caroline A., Wilson, Francis X., Davies, Kay E., Muntoni, Francesco, Tinsley, Jonathon
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4790853/
https://ncbi.nlm.nih.gov/pubmed/26974331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150818
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