Characterization of Recombinant Respiratory Syncytial Viruses with the Region Responsible for Type 2 T-Cell Responses and Pulmonary Eosinophilia Deleted from the Attachment (G) Protein

It is essential that preventative vaccines for respiratory syncytial virus (RSV) elicit balanced T-cell responses. Immune responses dominated by type 2 T cells against RSV antigens are believed to cause exaggerated respiratory tract disease and may also contribute to unwanted inflammation in the air...

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Detalhes bibliográficos
Main Authors: Elliott, Matthew B., Pryharski, Karin S., Yu, Qingzhong, Boutilier, L. A., Campeol, N., Melville, K., Laughlin, Todd S., Gupta, C. K., Lerch, Robert A., Randolph, Valerie B., LaPierre, Natisha A., Dack, Kristen M. Heers, Hancock, Gerald E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC479074/
https://ncbi.nlm.nih.gov/pubmed/15280453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.16.8446-8454.2004
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