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Integrated Self-Inactivating Lentiviral Vectors Produce Full-Length Genomic Transcripts Competent for Encapsidation and Integration

To make human immunodeficiency virus type 1 (HIV-1)-based vectors safer for use in the research and clinical setting, a significant modification to the HIV-1 genome has been the deletion of promoter and enhancer elements from the U3 region of the long terminal repeat (LTR). Vectors containing this d...

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Bibliografski detalji
Glavni autori: Logan, Aaron C., Haas, Dennis L., Kafri, Tal, Kohn, Donald B.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2004
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC479072/
https://ncbi.nlm.nih.gov/pubmed/15280451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.16.8421-8436.2004
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