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Profile of farletuzumab and its potential in the treatment of solid tumors

Folate receptor (FR) α expression in normal tissues is restricted to a subpopulation of epithelial cells. In contrast, FRα is overexpressed in epithelial ovarian cancer (EOC) and non-small-cell lung carcinoma. Therefore, FRα is considered a promising therapeutic target for EOC and non-small-cell lun...

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Publicat a:Onco Targets Ther
Autors principals: Sato, Seiya, Itamochi, Hiroaki
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4789847/
https://ncbi.nlm.nih.gov/pubmed/27022278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S98242
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