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Profile of panobinostat and its potential for treatment in solid tumors: an update

The histone deacetylase (HDAC) inhibitors have emerged as novel therapies for cancer. Panobinostat (LBH 589, Novartis Pharmaceuticals) is a pan-deacetylase inhibitor that is being evaluated in both intravenous and oral formulations across multiple tumor types. Comparable to the other HDACs, panobino...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Anne, Madhurima, Sammartino, Daniel, Barginear, Myra F, Budman, Daniel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3833618/
https://ncbi.nlm.nih.gov/pubmed/24265556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S30773
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