The regulatory element READ1 epistatically influences reading and language, with both deleterious and protective alleles

BACKGROUND: Reading disability (RD) and language impairment (LI) are heritable learning disabilities that obstruct acquisition and use of written and spoken language, respectively. We previously reported that two risk haplotypes, each in strong linkage disequilibrium (LD) with an allele of READ1, a...

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Détails bibliographiques
Publié dans:J Med Genet
Auteurs principaux: Powers, Natalie R, Eicher, John D, Miller, Laura L, Kong, Yong, Smith, Shelley D, Pennington, Bruce F, Willcutt, Erik G, Olson, Richard K, Ring, Susan M, Gruen, Jeffrey R
Format: Artigo
Langue:Inglês
Publié: BMJ Publishing Group 2016
Sujets:
Complex Traits
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4789805/
https://ncbi.nlm.nih.gov/pubmed/26660103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmedgenet-2015-103418
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