The regulatory element READ1 epistatically influences reading and language, with both deleterious and protective alleles

BACKGROUND: Reading disability (RD) and language impairment (LI) are heritable learning disabilities that obstruct acquisition and use of written and spoken language, respectively. We previously reported that two risk haplotypes, each in strong linkage disequilibrium (LD) with an allele of READ1, a...

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Detalhes bibliográficos
Publicado no:J Med Genet
Main Authors: Powers, Natalie R, Eicher, John D, Miller, Laura L, Kong, Yong, Smith, Shelley D, Pennington, Bruce F, Willcutt, Erik G, Olson, Richard K, Ring, Susan M, Gruen, Jeffrey R
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2016
Assuntos:
Complex Traits
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4789805/
https://ncbi.nlm.nih.gov/pubmed/26660103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmedgenet-2015-103418
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