Palmoplantar keratoderma in Slurp2-deficient mice

SLURP1, a member of the Ly6 protein family, is secreted by suprabasal keratinocytes. Mutations in SLURP1 cause a palmoplantar keratoderma (PPK) known as mal de Meleda. Another secreted Ly6 protein, SLURP2, is encoded by a gene located ~20 kb downstream from SLURP1. SLURP2 is produced by suprabasal k...

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Detalhes bibliográficos
Publicado no:J Invest Dermatol
Main Authors: Allan, Christopher M., Procaccia, Shiri, Tran, Deanna, Tu, Yiping, Barnes, Richard H., Larsson, Mikael, Allan, Bernard B., Young, Lorraine C., Hong, Cynthia, Tontonoz, Peter, Fong, Loren G., Young, Stephen G., Beigneux, Anne P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4789766/
https://ncbi.nlm.nih.gov/pubmed/26967477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2015.11.003
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