Kinetic ESI-MS Studies of Potent Anti-HIV Aptamers Based on the G-Quadruplex Forming Sequence d(TGGGAG)

[Image: see text] To investigate what properties make tetramolecular G-quadruplex ODNs good anti-HIV aptamers, we studied the stoichiometry and the self-assembly kinetics of the highly active 5′-end modified G-quadruplexes based on the d(TGGGAG) sequence. Our results demonstrate that the 5′-end conj...

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Argitaratua izan da:ACS Med Chem Lett
Egile Nagusiak: Romanucci, Valeria, Marchand, Adrien, Mendoza, Oscar, D’Alonzo, Daniele, Zarrelli, Armando, Gabelica, Valérie, Di Fabio, Giovanni
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Chemical Society 2016
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4789677/
https://ncbi.nlm.nih.gov/pubmed/26985311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.5b00408
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