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Telomere shortening leads to earlier age of onset in ALS mice

Telomere shortening has been linked to a variety of neurodegenerative diseases. Recent evidence suggests that reduced telomerase expression results in shorter telomeres in leukocytes from sporadic patients with amyotrophic lateral sclerosis (ALS) compared with healthy controls. Here, we have charact...

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Dades bibliogràfiques
Publicat a:Aging (Albany NY)
Autors principals: Linkus, Birgit, Wiesner, Diana, MeΔner, Martina, Karabatsiakis, Alexander, Scheffold, Annika, Rudolph, K. Lenhard, Thal, Dietmar R., Weishaupt, Jochen H., Ludolph, Albert C., Danzer, Karin M.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4789589/
https://ncbi.nlm.nih.gov/pubmed/26978042
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