Reversal of phenotypes of cellular senescence by pan-mTOR inhibition

Cellular senescence, a state of essentially irreversible proliferation arrest, serves as a potent tumour suppressor mechanism. However, accumulation of senescent cells with chronological age is likely to contribute to loss of tissue and organ function and organismal aging. A crucial biochemical modu...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Aging (Albany NY)
Asıl Yazarlar: Walters, Hannah E., Deneka-Hannemann, Sylwia, Cox, Lynne S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2016
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4789579/
https://ncbi.nlm.nih.gov/pubmed/26851731
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