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First microdeletion involving only the biotinidase gene that can cause biotinidase deficiency: A lesson for clinical practice

We report the first microdeletion (26 kb) of the biotinidase gene (BTD) that involves three of the four exons of the gene. This deletion further exemplifies the importance of performing microarray analysis or other methodologies for a deletion of the BTD gene when the enzymatic activity indicates lo...

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Publicado en:Mol Genet Metab Rep
Autor principal: Wolf, Barry
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4789387/
https://ncbi.nlm.nih.gov/pubmed/27014582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgmr.2016.02.006
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