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Comparative genomic analysis of toxin-negative strains of Clostridium difficile from humans and animals with symptoms of gastrointestinal disease

BACKGROUND: Clostridium difficile infections (CDI) are a significant health problem to humans and food animals. Clostridial toxins ToxA and ToxB encoded by genes tcdA and tcdB are located on a pathogenicity locus known as the PaLoc and are the major virulence factors of C. difficile. While toxin-neg...

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Detalhes bibliográficos
Publicado no:BMC Microbiol
Main Authors: Roy Chowdhury, Piklu, DeMaere, Matthew, Chapman, Toni, Worden, Paul, Charles, Ian G., Darling, Aaron E., Djordjevic, Steven P.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4789261/
https://ncbi.nlm.nih.gov/pubmed/26971047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-016-0653-3
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