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Non-essential role for cilia in coordinating precise alignment of lens fibres

The primary cilium, a microtubule-based organelle found in most cells, is a centre for mechano-sensing fluid movement and cellular signalling, notably through the Hedgehog pathway. We recently found that each lens fibre cell has an apically situated primary cilium that is polarised to the side of th...

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Detalhes bibliográficos
Publicado no:Mech Dev
Main Authors: Sugiyama, Yuki, Shelley, Elizabeth J., Yoder, Bradley K., Kozmik, Zbynek, May-Simera, Helen L., Beales, Philip L., Lovicu, Frank J., McAvoy, John W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4789115/
https://ncbi.nlm.nih.gov/pubmed/26825015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mod.2016.01.003
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