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Wnt-Frizzled Signaling Is Part of an FGF-Induced Cascade that Promotes Lens Fiber Differentiation

PURPOSE. It is well established that lens fiber differentiation depends on an FGF-initiated growth factor signaling cascade. Given that recent studies indicate Wnt-Frizzled/Planar Cell Polarity (Wnt-Fz/PCP) signaling has a role in coordinating the orientation and alignment of fibers, this study set...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Dawes, Lucy J., Sugiyama, Yuki, Tanedo, Ana S., Lovicu, Frank J., McAvoy, John W.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601884/
https://ncbi.nlm.nih.gov/pubmed/23385791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-11357
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