A Crosstalk between TGF-β/Smad3 and Wnt/β-Catenin Pathways Promotes Vascular Smooth Muscle Cell Proliferation

RATIONALE: Endovascular interventions performed for atherosclerotic lesions trigger excessive vascular smooth muscle cell (SMC) proliferation leading to intimal hyperplasia. Our previous studies show that following endovascular injury, elevated TGF-β/Smad3 promotes SMC proliferation and intimal hype...

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Udgivet i:Cell Signal
Main Authors: DiRenzo, Daniel M., Chaudhary, Mirnal A., Shi, Xudong, Franco, Sarah R., Zent, Joshua, Wang, Katie, Guo, Lian-Wang, Kent, K. Craig
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4788971/
https://ncbi.nlm.nih.gov/pubmed/26912210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2016.02.011
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