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The Voltage Activation of Cortical KCNQ Channels Depends on Global PIP2 Levels

The slow afterhyperpolarization (sAHP) is a calcium-activated potassium conductance with critical roles in multiple physiological processes. Pharmacological and genetic data suggest that KCNQ channels partly mediate the sAHP. However, these channels are not typically open within the observed voltage...

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Dettagli Bibliografici
Pubblicato in:Biophys J
Autori principali: Kim, Kwang S., Duignan, Kevin M., Hawryluk, Joanna M., Soh, Heun, Tzingounis, Anastasios V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4788708/
https://ncbi.nlm.nih.gov/pubmed/26958886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.01.006
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