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The Voltage Activation of Cortical KCNQ Channels Depends on Global PIP2 Levels

The slow afterhyperpolarization (sAHP) is a calcium-activated potassium conductance with critical roles in multiple physiological processes. Pharmacological and genetic data suggest that KCNQ channels partly mediate the sAHP. However, these channels are not typically open within the observed voltage...

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Dades bibliogràfiques
Publicat a:Biophys J
Autors principals: Kim, Kwang S., Duignan, Kevin M., Hawryluk, Joanna M., Soh, Heun, Tzingounis, Anastasios V.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4788708/
https://ncbi.nlm.nih.gov/pubmed/26958886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.01.006
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