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The Importance of Non-Nuclear AR Signaling in Prostate Cancer Progression and Therapeutic Resistance

The androgen receptor (AR) remains the major oncogenic driver of prostate cancer, as evidenced by the efficacy of androgen deprivation therapy (ADT) in naïve patients, and the continued effectiveness of second generation ADTs in castration resistant disease. However, current ADTs are limited to inte...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cell Signal
Auteurs principaux: Zarif, Jelani C., Miranti, Cindy K.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4788534/
https://ncbi.nlm.nih.gov/pubmed/26829214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2016.01.013
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