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The Importance of Non-Nuclear AR Signaling in Prostate Cancer Progression and Therapeutic Resistance

The androgen receptor (AR) remains the major oncogenic driver of prostate cancer, as evidenced by the efficacy of androgen deprivation therapy (ADT) in naïve patients, and the continued effectiveness of second generation ADTs in castration resistant disease. However, current ADTs are limited to inte...

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Bibliografiske detaljer
Udgivet i:Cell Signal
Main Authors: Zarif, Jelani C., Miranti, Cindy K.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4788534/
https://ncbi.nlm.nih.gov/pubmed/26829214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2016.01.013
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