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The Importance of Non-Nuclear AR Signaling in Prostate Cancer Progression and Therapeutic Resistance

The androgen receptor (AR) remains the major oncogenic driver of prostate cancer, as evidenced by the efficacy of androgen deprivation therapy (ADT) in naïve patients, and the continued effectiveness of second generation ADTs in castration resistant disease. However, current ADTs are limited to inte...

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Detalhes bibliográficos
Publicado no:Cell Signal
Main Authors: Zarif, Jelani C., Miranti, Cindy K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4788534/
https://ncbi.nlm.nih.gov/pubmed/26829214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2016.01.013
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