Citrullination-acetylation interplay guides E2F-1 activity during the inflammatory response

Peptidyl arginine deiminase 4 (PAD4) is a nuclear enzyme that converts arginine residues to citrulline. Although increasingly implicated in inflammatory disease and cancer, the mechanism of action of PAD4 and its functionally relevant pathways remains unclear. E2F transcription factors are a family...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Sci Adv
Main Authors: Ghari, Fatemeh, Quirke, Anne-Marie, Munro, Shonagh, Kawalkowska, Joanna, Picaud, Sarah, McGouran, Joanna, Subramanian, Venkataraman, Muth, Aaron, Williams, Richard, Kessler, Benedikt, Thompson, Paul R., Fillipakopoulos, Panagis, Knapp, Stefan, Venables, Patrick J., La Thangue, Nicholas B.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Association for the Advancement of Science 2016
נושאים:
Research Articles
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4788482/
https://ncbi.nlm.nih.gov/pubmed/26989780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1501257
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