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Interplay between lysine methylation and Cdk phosphorylation in growth control by the retinoblastoma protein
As a critical target for cyclin-dependent kinases (Cdks), the retinoblastoma tumour suppressor protein (pRb) controls early cell cycle progression. We report here a new type of regulation that influences Cdk recognition and phosphorylation of substrate proteins, mediated through the targeted methyla...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3025457/ https://ncbi.nlm.nih.gov/pubmed/21119616 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.311 |
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