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Redundant Regulation of Cdk1 Tyrosine Dephosphorylation in Saccharomyces cerevisiae

Cdk1 activity drives both mitotic entry and the metaphase-to-anaphase transition in all eukaryotes. The kinase Wee1 and the phosphatase Cdc25 regulate the mitotic activity of Cdk1 by the reversible phosphorylation of a conserved tyrosine residue. Mutation of cdc25 in Schizosaccharomyces pombe blocks...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Kennedy, Erin K., Dysart, Michael, Lianga, Noel, Williams, Elizabeth C., Pilon, Sophie, Doré, Carole, Deneault, Jean-Sebastien, Rudner, Adam D.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4788127/
https://ncbi.nlm.nih.gov/pubmed/26715668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.115.182469
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