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PGC-1α Induces Human RPE Oxidative Metabolism and Antioxidant Capacity
PURPOSE: Oxidative stress and metabolic dysregulation of the RPE have been implicated in AMD; however, the molecular regulation of RPE metabolism remains unclear. The transcriptional coactivator, peroxisome proliferator-activated receptor-gamma coactivator 1α (PGC-1α) is a powerful mediator of mitoc...
Gardado en:
| Publicado en: | Invest Ophthalmol Vis Sci |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Association for Research in Vision and Ophthalmology
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4788093/ https://ncbi.nlm.nih.gov/pubmed/26962700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.15-17758 |
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