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Dissecting the target specificity of RNase H recruiting oligonucleotides using massively parallel reporter analysis of short RNA motifs

Processing and post-transcriptional regulation of RNA often depend on binding of regulatory molecules to short motifs in RNA. The effects of such interactions are difficult to study, because most regulatory molecules recognize partially degenerate RNA motifs, embedded in a sequence context specific...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Rukov, Jakob Lewin, Hagedorn, Peter H., Høy, Isabel Bro, Feng, Yanping, Lindow, Morten, Vinther, Jeppe
Format: Artigo
Language:Inglês
Published: Oxford University Press 2015
Subjects:
RNA
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4787823/
https://ncbi.nlm.nih.gov/pubmed/26220183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv759
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