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Molecular basis for the substrate specificity and catalytic mechanism of thymine-7-hydroxylase in fungi

TET proteins play a vital role in active DNA demethylation in mammals and thus have important functions in many essential cellular processes. The chemistry for the conversion of 5mC to 5hmC, 5fC and 5caC catalysed by TET proteins is similar to that of T to 5hmU, 5fU and 5caU catalysed by thymine-7-h...

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Bibliografski detalji
Izdano u:Nucleic Acids Res
Glavni autori: Li, Wenjing, Zhang, Tianlong, Ding, Jianping
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4787775/
https://ncbi.nlm.nih.gov/pubmed/26429971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv979
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