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Molecular basis for the substrate specificity and catalytic mechanism of thymine-7-hydroxylase in fungi
TET proteins play a vital role in active DNA demethylation in mammals and thus have important functions in many essential cellular processes. The chemistry for the conversion of 5mC to 5hmC, 5fC and 5caC catalysed by TET proteins is similar to that of T to 5hmU, 5fU and 5caU catalysed by thymine-7-h...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4787775/ https://ncbi.nlm.nih.gov/pubmed/26429971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv979 |
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