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A novel mode of nuclease action is revealed by the bacterial Mre11/Rad50 complex
The Mre11/Rad50 complex is a central player in various genome maintenance pathways. Here, we report a novel mode of nuclease action found for the Escherichia coli Mre11/Rad50 complex, SbcC(2)/D(2) complex (SbcCD). SbcCD cuts off the top of a cruciform DNA by making incisions on both strands and cont...
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| 發表在: | Nucleic Acids Res |
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| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4787754/ https://ncbi.nlm.nih.gov/pubmed/26319016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv855 |
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