Bcl-2 is a critical mediator of intestinal transformation

Intestinal tumour formation is generally thought to occur following mutational events in the stem cell pool. However, active NF-κB signalling additionally facilitates malignant transformation of differentiated cells. We hypothesized that genes shared between NF-κB and intestinal stem cell (ISCs) sig...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: van der Heijden, Maartje, Zimberlin, Cheryl D., Nicholson, Anna M., Colak, Selcuk, Kemp, Richard, Meijer, Sybren L., Medema, Jan Paul, Greten, Florian R., Jansen, Marnix, Winton, Douglas J., Vermeulen, Louis
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786877/
https://ncbi.nlm.nih.gov/pubmed/26956214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10916
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