Large Conformational Changes of Insertion 3 in Human Glycyl-tRNA Synthetase (hGlyRS) during Catalysis

Glycyl-tRNA synthetase (GlyRS) is the enzyme that covalently links glycine to cognate tRNA for translation. It is of great research interest because of its nonconserved quaternary structures, unique species-specific aminoacylation properties, and noncanonical functions in neurological diseases, but...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Deng, Xiangyu, Qin, Xiangjing, Chen, Lei, Jia, Qian, Zhang, Yonghui, Zhang, Zhiyong, Lei, Dongsheng, Ren, Gang, Zhou, Zhihong, Wang, Zhong, Li, Qing, Xie, Wei
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2016
Teme:
Molecular Biophysics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786711/
https://ncbi.nlm.nih.gov/pubmed/26797133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.679126
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