Catch-bond mechanism of the bacterial adhesin FimH

Ligand–receptor interactions that are reinforced by mechanical stress, so-called catch-bonds, play a major role in cell–cell adhesion. They critically contribute to widespread urinary tract infections by pathogenic Escherichia coli strains. These pathogens attach to host epithelia via the adhesin Fi...

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Vydáno v:Nat Commun
Hlavní autoři: Sauer, Maximilian M., Jakob, Roman P., Eras, Jonathan, Baday, Sefer, Eriş, Deniz, Navarra, Giulio, Bernèche, Simon, Ernst, Beat, Maier, Timm, Glockshuber, Rudi
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786642/
https://ncbi.nlm.nih.gov/pubmed/26948702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10738
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