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Localization of tamoxifen in human breast cancer tumors by MALDI mass spectrometry imaging

BACKGROUND: Tamoxifen is used in endocrine treatment of breast cancer to inhibit estrogen signaling. A set of stratified ER-positive and ER-negative tumor sections was subjected to manual deposition of tamoxifen solution in order to investigate its spatial distribution upon exposure to interaction w...

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Detalhes bibliográficos
Publicado no:Clin Transl Med
Main Authors: Végvári, Ákos, Shavkunov, Alexander S., Fehniger, Thomas E., Grabau, Dorthe, Niméus, Emma, Marko-Varga, György
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786513/
https://ncbi.nlm.nih.gov/pubmed/26965929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40169-016-0090-9
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